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Phase hopitalcroixdusud.com its instillation into the eye.

Three methods have been employed to induce phase transition on the eye surface: Cellulose acetate phthalate forms a pH-triggered phase transition system, which shows a very low viscosity up to pH 5. The half-life of residence on the rabbit corneal surface was approximately 400 seconds compared to 40 seconds for saline. However, such systems are characterized by a high polymer concentration, Kamagra Soft Online France, and the low pH of the instilled solution may cause discomfort to the patient. Gellan gum is an anionic polysaccharide formulated in aqueous solution, which forms clear gels under the influence of an increase in ionic strength. The gellation increases proportionally to the amount of either monovalent or divalent cations.

The reflex tearing, which often leads to a dilution of ophthalmic solutions, further enhances the viscosity of the gellan gum by increasing the tear volume and thus the increased cation concentration.

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